Francois [Francesco] Santini (fl. 1776 - 1784) was an Italian cartographer and map publisher based in Venice. Francois Santini is often confused with Paolo Santini, a Venetian engraver also known for religious prints and cartographic work. Scholarship is unclear whether these are related individuals, the same person, or completely unrelated. Both cartographers were active in roughly the same period and reissued maps of earlier French cartographers ranging from Vaugondy, to Jaillot, to De L'Isle, to D'Anville. Both cartographers also worked with the Venetian Remondini publishing house. Paolo was possibly an Abbot. Francois Santini seems to have worked extensively in Paris and is associated with several French cartographers of the late 18th century including Rigobert Bonne. His offices in Paris were located at Rue St. Justine pres de L'Eglise. In the 1780s Francois Santini published an atlas, the Remondini Atlas Universel, in conjunction with the Remondini family of Venice. The Library of Congress associates this work with Paolo Santini - leading to still more confusion.